Organic Botanical Pesticides & Biological Fertilizers

Organic Botanical Pesticides & Biological Fertilizers

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Emodin

Emodin

Emodin is an orange-yellow long needle-like crystal. It crystallizes in  orange in acetone.
Product Details

Emodin is an orange-yellow long needle-like crystal. It crystallizes in orange in acetone. It crystallizes in methanol and has a melting point of 256 ° C to 257 ° C. It has a special reaction of hydrazine, is almost insoluble in water, and is soluble in ethanol and alkali solution. Emodin is the dried rhizome and root of Polygonum cuspidatum. The rhizome of palm rhubarb is a plant-type agent. The physiological activity of Emodin determines that it can be used not only in medical treatment, but also in health care and household chemicals. If it is used in hair care and skin care products, it is also incorporated into natural pigments. Abroad, people use it as a laxative.

Clinical Application

Oral Emodin is easily absorbed in the intestine. After 2 to 3 hours, the blood reaches the highest concentration, and then slowly decreases. The urine and bile reach a peak 4 to 8hours after taking the drug . The urine can be discharged for 2 days in the body. Distribution of liver and kidney is the most. It has also been used as an injection for muscle and intravenous injections.

After Emodin is absorbed, chrysophanol is excreted from the kidney, which turns the acidic urine into a brownish yellow color, which causes the alkaline urine to turn purple.

Clinically, Emodin is used to treat tumors, mainly for tumors such as leukemia and stomach cancer, and the most commonly used is for bacteriostatic. It is against many bacteria such as various staphylococcus, hemolytic streptococcus, diphtheria bacillus, cholera isolates, Escherichia coli, Pseudomonas aeruginosa, dermatophytes, Bacillus subtilis, Mycobacterium phlei, Neisseria gonorrhoeae, Charobacter, and grasses. , typhoid bacillus, dysentery bacilli, etc. have inhibitory effects. Among them, Staphylococcus, Neisseria gonorrhoeae, Streptococcus are more effective. This product is also effective against fungi, viruses, and protozoa. At the same time, it also has diuretic, choleretic, antispasmodic, lowering blood pressure and suppressing immune function.

Modern clinical use in almost all subjects, such as treatment of Japanese encephalitis and mumps, typhoid fever, dysentery, urinary tract infection, gonorrhea, pneumonia, cellulitis, suppurative skin disease, otitis media, vasculitis, etc., compatible with other drugs Treatment of acute and subacute appendicitis, burns, poliomyelitis, eczema and skin infections caused by several fungi, in addition to treatment of hepatitis, mites, stomatitis, lip ulcers, dyspepsia, hypertension and arteriosclerosis, therefore, Emodin is clinical The application is extremely wide.

Recent data suggest that Emodin can affect the proliferation of keratinocytes in vitro; it can prevent restenosis after coronary interventional therapy. It can inhibit human kidney fibroblasts. Although Emodin is less toxic, it is contraindicated in pregnant women because it can cause miscarriage in pregnant women.

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